5-Methyluridine 1463-10-1 CAS NO.1463-10-1

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5-Methyluridine is a nucleoside derivative of uridine, which is one of the basic building blocks of RNA (ribonucleic acid). It is characterized by a methyl group (-CH?) attached to the 5th carbon of the uridine's pyrimidine ring. Its chemical formula is C?H?N?O?.

Key Points about 5-Methyluridine:

1. Biological Role: In biological systems, 5-methyluridine is involved in the modification of RNA molecules. It can be found in tRNA (transfer RNA) where it contributes to the stability and function of tRNA by helping to maintain the correct structure and function of the RNA molecule.

2. Function: The methylation of uridine can affect the folding and stability of RNA molecules, which in turn can influence protein synthesis and other cellular processes. 5-methyluridine is considered a form of post-transcriptional modification, which plays a role in the regulation of gene expression and RNA processing.

3. Research and Therapeutic Uses: While 5-methyluridine itself is not typically used as a therapeutic agent, research into nucleoside analogs and modifications like 5-methyluridine can provide insights into RNA function and potentially lead to the development of novel therapeutic strategies. For example, understanding RNA modifications can help in designing drugs that target specific RNA molecules or processes.

4. Occurrence: It is a naturally occurring compound found in various organisms and plays a role in the biological functions of RNA.

5-Methyluridine and its derivatives are important in the study of RNA biology and can have implications for understanding cellular processes and developing new treatments.