China Suppliers hot selling nootkatone CAS 4674-50-4 with best quality CAS NO.4674-50-4

Professional supplier Xylobiose CAS 6860-47-5 with superior quality

Company profile

Wuhan Fortuna Chemical Co.,Ltd established in 2006, is a big integrative chemical enterprise being engaged in Pharmaceutical & its intermediates, Food/Feed additives, Fine chemicals in distributing the products of our own company and affiliated enterprises, are the members of Hubei E-commerce Chamber.

Our company has professional persons who major in chemical R&D and sicentific management, supply fine chemical products with high quality and close service, also supply custom-tailored products according to our clients’ requirement.

We have a positive and self-motivated management work team with a common philosophy, caring and commitment through teamwork, our team strive to achieve success in delighting our clients and ourselves. 

Since Wuhan Fortuna Chemical Co., Ltd founded, we continuously innovate our products and improve our service, sales network. Hence, we initiate the first sale mode on net in China, which is the retail trade of small package bring along wholesale of diversified management modes. Our products are exported widely to South Korea, Vietnam, Australia, Europe and South America, highly recommended by our clients.

We insist on the management creed “Market is our compass, Quality is our life, Credit is our soul”. Clients’ trust is our forward powder, their satisfaction is our struggling goal.

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Nootkatone is a natural organic compound classified as a sesquiterpene, renowned for its distinctive citrus aroma and diverse industrial applications. Here’s a detailed overview:

1. Source & Chemical Properties

• Natural Sources:

  • Primarily found in grapefruit peel and juice (Citrus paradisi), with smaller amounts in the essential oils of Alaska yellow cedar (Callitropsis nootkatensis, formerly Chamaecyparis nootkatensis).

  • Its name derives from the Nootka cypress tree.

• Chemical Structure:

  • Formula: C??H??O (a bicyclic sesquiterpene ketone).

  • Characterized by a strong, fresh citrus scent with woody and spicy undertones.

2. Key Applications

① Fragrance & Flavoring

Widely used in food, beverages, cosmetics, and perfumes to impart natural citrus notes (e.g., grapefruit-flavored drinks).

Preferred as a natural alternative to synthetic flavoring agents.

② Insect Repellent

EPA-Approved: In 2020, the U.S. Environmental Protection Agency (EPA) registered nootkatone as a biobased insect repellent effective against mosquitoes, ticks, and other disease-carrying insects.

Safer for humans and pets compared to synthetic chemicals like DEET.

③ Agriculture & Pest Control

Acts as a natural pesticide against agricultural pests (e.g., termites, aphids), supporting eco-friendly farming practices.

④ Pharmaceutical Research

Studied for potential antimicrobial, anti-inflammatory, and antioxidant properties, with possible applications in drug development.

3. Production & Commercialization

• Extraction Methods:

  • Traditionally extracted from grapefruit or cedar, but low yields make it costly.

  • Biosynthesis: Modern methods use engineered yeast or bacteria (e.g., Saccharomyces cerevisiae) to produce nootkatone sustainably via fermentation.

• Key Producers:

  • Companies like Evolva (Switzerland) and Conagen (USA) specialize in microbial fermentation for large-scale production.

4. Advantages & Challenges

• Strengths:

  • Natural, biodegradable, and low toxicity.

  • Multifunctional uses (flavor, pest control, healthcare).

• Challenges:

  • High production costs for natural extraction; reliance on biotech for scalability.

  • Market competition with established synthetic repellents (e.g., DEET).

5. Future Outlook

Nootkatone is gaining traction in green chemistry, public health (e.g., Lyme disease prevention), and sustainable agriculture.

The U.S. Centers for Disease Control and Prevention (CDC) and military have explored its use in eco-friendly insect control solutions.

For updated research, refer to journals like Journal of Agricultural and Food Chemistry or the EPA’s official guidelines on biopesticides.