China Suppliers High quality Glyoxylic acid monohydrate CAS 563-96-2 CAS NO.563-96-2

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Company profile

Wuhan Fortuna Chemical Co.,Ltd established in 2006, is a big integrative chemical enterprise being engaged in Pharmaceutical & its intermediates, Food/Feed additives, Fine chemicals in distributing the products of our own company and affiliated enterprises, are the members of Hubei E-commerce Chamber.

Our company has professional persons who major in chemical R&D and sicentific management, supply fine chemical products with high quality and close service, also supply custom-tailored products according to our clients’ requirement.

We have a positive and self-motivated management work team with a common philosophy, caring and commitment through teamwork, our team strive to achieve success in delighting our clients and ourselves. 

Since Wuhan Fortuna Chemical Co., Ltd founded, we continuously innovate our products and improve our service, sales network. Hence, we initiate the first sale mode on net in China, which is the retail trade of small package bring along wholesale of diversified management modes. Our products are exported widely to South Korea, Vietnam, Australia, Europe and South America, highly recommended by our clients.

We insist on the management creed “Market is our compass, Quality is our life, Credit is our soul”. Clients’ trust is our forward powder, their satisfaction is our struggling goal.

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Glyoxylic Acid Monohydrate (CAS 563-96-2): A Detailed Overview

1. Chemical Identity

IUPAC Name: Oxoacetic acid monohydrate

Chemical Formula: C?H?O?·H?O

CAS Number: 563-96-2 (monohydrate form)

Molecular Weight: 108.05 g/mol

Structure: An alpha-keto acid (keto group adjacent to carboxylic acid) with one water molecule of crystallization.

2. Physical Properties

Appearance: White crystalline solid.

Solubility: Highly soluble in water, slightly soluble in ethanol.

Melting Point: ~50–52°C (monohydrate decomposes upon heating).

pH: Strongly acidic (pKa ~3.18 for the carboxylic acid group).

Hygroscopicity: Absorbs moisture from the air.

3. Key Applications

Organic Synthesis

Pharmaceuticals: Precursor for drugs like allantoin (skin protectant) and vanillin (flavoring agent).

Agrochemicals: Used in herbicides (e.g., glyphosate intermediates) and plant growth regulators.

Polymers: Cross-linking agent in resins and adhesives (e.g., urea-glyoxal resins).

Cosmetics

Chemical Peels: Acts as a keratolytic agent, promoting exfoliation (less common than glycolic acid but used in specialized formulations).

Biochemistry

Enzyme Studies: Substrate or inhibitor in studies of glyoxylate cycle enzymes.

4. Reactivity & Stability

• Reactivity:

  • Undergoes nucleophilic addition (e.g., with amines to form Schiff bases).

  • Participates in condensation reactions (e.g., with urea to produce hydantoin).

• Stability:

  • Sensitive to heat, light, and oxidation.

  • Store in cool, dry conditions (see storage guidelines below).

5. Safety & Handling

• Hazards:

  • Corrosive: Causes skin/eye irritation (wear gloves, goggles).

  • Inhalation Risk: Dust may irritate respiratory tract.

• Environmental Impact: Biodegradable but toxic to aquatic life at high concentrations.

• Regulatory Status:

  • Listed under EU REACH regulations.

  • Cosmetic use is restricted (check local guidelines for concentration limits).

6. Comparison to Similar Compounds

7. Storage Recommendations

Store in airtight containers away from light and moisture.

Ideal temperature: 2–8°C (refrigeration recommended for long-term stability).

8. Industrial Suppliers

Commonly available from chemical suppliers like:

Sigma-Aldrich

TCI Chemicals

Alfa Aesar

Conclusion

Glyoxylic acid monohydrate is a versatile, reactive compound with broad applications in organic synthesis, agrochemicals, and niche cosmetic formulations. Its strong acidity and hygroscopic nature require careful handling, but its role as a precursor in pharmaceuticals and polymers makes it industrially valuable. Always verify regulatory compliance for specific uses.