China Supplier Tropisetron Hcl cas 105826-92-4 with high quality CAS NO.105826-92-4

1.High quality : the purity is 99% min . through multiple producing procedures. 2.Competitive price : low price because of our skilled production technolpgy ,save the production cost at most , and give big profit room to our customers 3.Safe and fast delivery : we have professional shipment team for each package , the best shipping lines , each package can reach safe ly and fastly . 4.Varied shipment methods : We can ship via EMS , HKEMS ,FEDEX ,DHL ,TNT,UPS for small packages (from 100g to 10kgs ), and by air or by sea for big quantity . Once ship out , there is a tracking number for your package , you can follow it online, more convenient 5.Good service : 100g order or 100kgs order , we will treat as the same . thinking of all possible problems for the customer ,giving the best suggestions , and good professional guide for the products.

Tropisetron Hydrochloride is a 5-HT3 receptor antagonist used primarily to prevent and treat nausea and vomiting induced by chemotherapy, radiotherapy, or postoperative recovery.

Key Details

Mechanism: Blocks serotonin (5-HT3) receptors in the gut and central nervous system, inhibiting the vomiting reflex.

• Uses:

  • Chemotherapy-induced nausea/vomiting (CINV).

  • Postoperative nausea/vomiting (PONV).

• Administration: Available as oral tablets, injections, or IV infusions.

• Dosage:

  • Adults: Typically 5 mg once daily (oral or IV), adjusted based on clinical need.

  • Pediatric use: Limited; dose determined by weight and condition.

Side Effects

Common: Headache, constipation, dizziness.

Rare: QT interval prolongation (cardiac risk), allergic reactions.

Advantages

Long half-life (~8 hours), allowing once-daily dosing.

Effective for both acute and delayed nausea/vomiting.

Precautions

Avoid in patients with heart rhythm disorders (due to QT prolongation risk).

Use cautiously with other serotonergic drugs (risk of serotonin syndrome).

Comparison to Other 5-HT3 Antagonists

Similar to ondansetron and granisetron but with a longer duration of action.

Note: Prescription-only; adherence to dosing guidelines is critical to minimize adverse effects.