Tetrahydro-2H-pyran-4-yl methanesulfonate CAS 134419-59-3 CAS NO.134419-59-3

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Wuhan Fortuna Chemical Co.,Ltd established in 2006, is a big integrative chemical enterprise being engaged in Pharmaceutical & its intermediates, Food/Feed additives, Fine chemicals in distributing the products of our own company and affiliated enterprises, are the members of Hubei E-commerce Chamber.

Our company has professional persons who major in chemical R&D and sicentific management, supply fine chemical products with high quality and close service, also supply custom-tailored products according to our clients’ requirement.

We have a positive and self-motivated management work team with a common philosophy, caring and commitment through teamwork, our team strive to achieve success in delighting our clients and ourselves. 

Since Wuhan Fortuna Chemical Co., Ltd founded, we continuously innovate our products and improve our service, sales network. Hence, we initiate the first sale mode on net in China, which is the retail trade of small package bring along wholesale of diversified management modes. Our products are exported widely to South Korea, Vietnam, Australia, Europe and South America, highly recommended by our clients.

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Tetrahydro-2H-pyran-4-yl methanesulfonate is a sulfonate ester derivative of tetrahydropyran (THP), a six-membered oxygen-containing saturated ring. Its structure consists of a tetrahydropyran ring with a methanesulfonate (mesylate) group (-SO?CH?) attached to the 4-position of the ring. Key points:

1. Structure:

   THP ring: A cyclic ether (C?H??O) with oxygen at position 1.                                                                                                       Mesylate group: A strong leaving group (CH?SO??) at position 4.

2. Role in Organic Chemistry:

   Acts as a reagent or intermediate in organic synthesis.                                                                                                                            The mesylate group facilitates nucleophilic substitution reactions (e.g., SN2), enabling the introduction of the THP moiety into other molecules.

3. Applications:

   Used to synthesize THP-protected compounds, often in alcohol protection/deprotection strategies.                                                  Common in pharmaceuticals, agrochemicals, or materials science for controlled functionalization.

4. Safety:

   Methanesulfonate derivatives are typically corrosive; handle with protective equipment.

This compound is valued for its reactivity in constructing complex molecules via substitution or activation of the THP scaffold.