China Suppliers 2,6-Diaminopyridine powder best price CAS 141-86-6 Used for pharmaceutical raw materials CAS NO.141-86-6

Wuhan Fortuna Chemical Co.,Ltd is a professional integrative chemical enterprise with 18 years exporting experience,which is being engaged in Pharmaceutical and its intermediates, Food and Feed additives, Fine chemicals.

2,6-Diaminopyridine is an organic compound with the molecular formula C?H?N?. Here's a detailed overview:

Chemical Structure

• It consists of a pyridine ring (a six-membered aromatic ring with one nitrogen atom) substituted with two amine groups (-NH?) at the 2 and 6 positions relative to the nitrogen (position 1). This arrangement gives the molecule symmetry, with the amines positioned opposite each other across the ring.

Physical Properties

• Appearance: Typically a white to off-white crystalline solid.

• Solubility: Moderately soluble in water due to hydrogen bonding from the amine groups. More soluble in polar organic solvents (e.g., ethanol, DMSO).

• Melting Point: Exact values vary, but it is solid at room temperature.

Synthesis

• Prepared via nitration of pyridine derivatives followed by reduction, or through direct amination using reagents like ammonia under controlled conditions. Specific methods depend on the desired substitution pattern.

Applications

1. Pharmaceuticals:

   • Acts as a precursor in synthesizing drugs, particularly those targeting neurological conditions (e.g., analogues of 4-aminopyridine used in multiple sclerosis).

2. Coordination Chemistry:

   • Serves as a chelating ligand for metal ions (e.g., Cu²?, Fe³?), leveraging its pyridine nitrogen and amine groups to form stable complexes.

3. Materials Science:

   • Used in polymers, dendrimers, or supramolecular assemblies due to its ability to participate in hydrogen bonding and crosslinking.

4. Agrochemicals and Dyes:

   • Intermediate in the synthesis of herbicides, insecticides, or colorants.

Safety and Handling

• Toxicity: May be harmful if inhaled, ingested, or absorbed through the skin. Causes irritation to eyes, skin, and respiratory system.

• Precautions: Use protective equipment (gloves, goggles) and work in a well-ventilated area. Proper disposal is essential to avoid environmental contamination.

Key Features

• Combines aromaticity with nucleophilic amine groups, making it reactive in electrophilic substitution and metal coordination.

• Symmetrical structure enhances its utility in creating ordered molecular architectures.

This compound bridges organic synthesis, medicinal chemistry, and materials science, highlighting its versatility in research and industrial applications.