China Suppliers high quality Framycetin sulphate CAS 4146-30-9 with good price CAS NO.4146-30-9

Professional supplier Framycetin sulphate CAS 4146-30-9 with superior quality

Company profile

Wuhan Fortuna Chemical Co.,Ltd established in 2006, is a big integrative chemical enterprise being engaged in Pharmaceutical & its intermediates, Food/Feed additives, Fine chemicals in distributing the products of our own company and affiliated enterprises, are the members of Hubei E-commerce Chamber.

Our company has professional persons who major in chemical R&D and sicentific management, supply fine chemical products with high quality and close service, also supply custom-tailored products according to our clients’ requirement.

We have a positive and self-motivated management work team with a common philosophy, caring and commitment through teamwork, our team strive to achieve success in delighting our clients and ourselves. 

Since Wuhan Fortuna Chemical Co., Ltd founded, we continuously innovate our products and improve our service, sales network. Hence, we initiate the first sale mode on net in China, which is the retail trade of small package bring along wholesale of diversified management modes. Our products are exported widely to South Korea, Vietnam, Australia, Europe and South America, highly recommended by our clients.

We insist on the management creed “Market is our compass, Quality is our life, Credit is our soul”. Clients’ trust is our forward powder, their satisfaction is our struggling goal.

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Framycetin sulfate is an aminoglycoside antibiotic derived from Streptomyces bacteria, specifically identified as Neomycin B in its sulfate salt form. Here's a structured overview:

Drug Class:

Aminoglycoside antibiotic, closely related to neomycin. It is a component of the neomycin complex, which also includes Neomycin C and Neomycin A.

Mechanism of Action:

Inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit, leading to misreading of mRNA and cell death. Effective against Gram-negative bacteria (e.g., E. coli, Klebsiella) and some Gram-positive bacteria.

Uses:

Topical applications to treat superficial infections:

Skin infections (e.g., cuts, burns, infected eczema).                                                                                                                                                        Eye infections (conjunctivitis).                                                                                                                                                                                          Ear infections (otitis externa).                                                                                                                                                                                            Often combined with other antibiotics (e.g., gramicidin, dexamethasone) in creams, ointments, or drops (e.g., Soframycin®, Neosporin® variants).

Formulation:

Administered as a sulfate salt to enhance solubility and stability in topical preparations.

Side Effects:

Local reactions: Irritation, redness, itching.

Allergic reactions: Contact dermatitis (rare but possible).

Caution: Prolonged use on broken skin may lead to systemic absorption, risking ototoxicity or nephrotoxicity (though rare with topical use).

Resistance & Precautions:

Not effective against anaerobic bacteria or Pseudomonas aeruginosa.

Resistance can develop with misuse; avoid over-the-counter prolonged use.

Key Note:

Framycetin sulfate is distinct from systemic aminoglycosides (e.g., gentamicin) due to its localized application, minimizing severe side effects. Always used under medical guidance to prevent resistance.