Manufacture favorable price high quality Tranilast Cas 53902-12-8 with fast delivery CAS NO.53902-12-8

Unique advantages for Tranilast Cas 53902-12-8

Product Name:    Tranilast
Synonyms:    2-((3-(3,4-dimethoxyphenyl)-1-oxo-2-propenyl)amino)-benzoicaci;n-(3,4-dimethoxycinnamoyl)-anthranilicaci;n-5’;rizaben;SB-252218;N-(3',4'-DIMETHOXYCINNAMOYL)ANTHRANILIC ACID;Tranilast - CAS 53902-12-8 - Calbiochem;2-[[3-(3,4-DIMETHOXYPHENYL)-1-OXO-2-PROPENYL]AMINO] BENZOIC ACID
CAS:    53902-12-8
MF:    C18H17NO5
MW:    327.33
EINECS:    
Product Categories:    PEXID;Inhibitors;Angiogenesis and Metastasis;Amines;Aromatics;Intermediates & Fine Chemicals;Angiotensin;Pharmaceuticals
Mol File:    53902-12-8.mol

 

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Manufacture favorable price high quality Tranilast Cas 53902-12-8 with fast delivery

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53902-12-8

Tranilast

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Product Name	Tranilast
Synonyms	2-[[3-(3,4-DIMETHOXYPHENYL)-1-OXO-2-PROPENYL]AMINO]  BENZOIC ACID;TRANILAST;2-((3-(3,4-dimethoxyphenyl)-1-oxo-2-  propenyl)amino)-benzoicaci;n-(3,4-dimethoxycinnamoyl)-  anthranilicaci;n-5’;rizaben;SB-252218
CAS No.	53902-12-8
EINECS	N/A
MF	C18H17NO5
MW	327.33
Appearance	Powder
Melting Point	166.2-168.2 °C(lit.)
Loss on drying	≤0.5%
Heavy Metals	≤10ppm
Purity	99%

Uses    coronary vasodilator
Uses    Tranilast is a compound that exhibits anti-inflammatory and immunomodulatory effects by inhibiting lipid mediator and cytokine release from inflammatory cells and interfering with PDGF- and TGF-β1-induced proliferation and migration of vascular medial smooth muscle cells. Tranilast suppresses production of prostaglandin D2 (IC50 = 0.1 mM), prostaglandin E2 (IC50 = ~1-20 μM), thromboxane B2 (IC50 = ~10-50 μM), TGF-β1 (IC50 = ~100-200 μM), and interleukin-8 (IC50 = ~100 μM) in in vitro models as well as attenuates of the proinflammatory activity of human monocytes. While originally marketed as an antiallergenic drug, the efficacy of tranilast in preventing restenosis after percutaneous coronary intervention has been tested in a large-scale clinical trial. Additionally, tranilast inhibits VEGF-induced angiogenetic activities (i.e., proliferation, migration and tube formation of vascular endothelial cells) with IC50 values of 22, 18 and 193 μM, which may prove therapeutic for various retinal diseases.

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Unique advantages for Tranilast Cas 53902-12-8

 

Guaranteed the purity

High quality & competitive price

Quality control

Fast feedback 

Prompt shipment

 

 

 

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About US:

      Wuhan Fortuna Chemical Co., Ltd, located in the predominant Wuhan Citywhere is a traffic hinge of China,is a big integrative chemical enterprise being engaged in producing and developing pharmaceutical & its intermediates, food additive  and plant extract, and in distributing the produc ts of our own company and affiliated enterprises.

      Our company has professional staff who deal with chemical R&D and scientific management, and holds several sets of analyzing instruments with high efficiency and high sensitivity, such as HPLC, GC and Spectrophotometer. Meanwhile, we possess of complete Q.A. and Q.C. system, supply chemical products with good quality and custom-tailored products according to our clients’ requirement.

      Since Fortuna Chemical foundation, we continuously innovate our products and improve our service, sales network. Hence, we initiate the first sales mode on net in China, which is the retail trade of small package bring along wholesale of diversified management modes. Our products are distributed to Japan, USA, Europe and Southeast of Asia, highly recommended by our clients.

      We Fortuna insist on the management creed“ Market is our compass, Quality is our life, Credit is our soul”. Clients’ trust is our forward power, their satisfaction is our struggling goal.

 

 

 

 

FAQ:

 

Q1:Are you a trader

No,We have our own factory  located in Wuhan,Hubei,and specilized in  all kinds of chemical products.

Q2:Could you please provide some samples

Yes,of course.It's my pleasure to provide  you samples.

Q3:How should I pay

We accept various payment ways such as L/C,T/T, and Money Gram.

Q4:Do you have stock

As we know,most customers prefer stock,so we will try to keep stock for chemical products.

Q5:What is your MOQ

In order to provide best support to our customers,our company do not regulate the strict MOQ.