Factory supply Tetracycline hydrochloride Cas 64-75-5 with high quality low price CAS NO.64-75-5

Professional supplier Tetracycline hydrochloride Cas 64-75-5 with superior quality

Company profile

Wuhan Fortuna Chemical Co.,Ltd established in 2006, is a big integrative chemical enterprise being engaged in Pharmaceutical & its intermediates, Food/Feed additives, Fine chemicals in distributing the products of our own company and affiliated enterprises, are the members of Hubei E-commerce Chamber.

Our company has professional persons who major in chemical R&D and sicentific management, supply fine chemical products with high quality and close service, also supply custom-tailored products according to our clients’ requirement.

We have a positive and self-motivated management work team with a common philosophy, caring and commitment through teamwork, our team strive to achieve success in delighting our clients and ourselves. 

Since Wuhan Fortuna Chemical Co., Ltd founded, we continuously innovate our products and improve our service, sales network. Hence, we initiate the first sale mode on net in China, which is the retail trade of small package bring along wholesale of diversified management modes. Our products are exported widely to South Korea, Vietnam, Australia, Europe and South America, highly recommended by our clients.

We insist on the management creed “Market is our compass, Quality is our life, Credit is our soul”. Clients’ trust is our forward powder, their satisfaction is our struggling goal.

our competitive advantage

Guaranteed purity

High quality & competitive price

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Tetracycline Hydrochloride is a broad-spectrum antibiotic belonging to the tetracycline class, formulated as the hydrochloride salt for enhanced solubility. Below is a structured overview:

1. Mechanism of Action

Inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit, blocking tRNA attachment. Effective against Gram-positive bacteria (e.g., Staphylococcus), Gram-negative bacteria (e.g., E. coli), Rickettsia, Mycoplasma, and Chlamydia.

2. Indications

• Common uses:

  • Acne (moderate-to-severe inflammatory cases).

  • Respiratory infections (e.g., pneumonia, bronchitis).

  • Urinary tract infections, skin/soft tissue infections.

  • Sexually transmitted infections (e.g., chlamydia, gonorrhea).

  • Rickettsial diseases (e.g., typhus).

3. Dosage & Administration

Forms: Tablets, capsules, or injectable solutions (oral or IV).

Dosage: Adults typically 250–500 mg every 6 hours (adjust per severity and guidelines).

• Key notes:

  • Take on an empty stomach (1 hour before or 2 hours after meals). Avoid concurrent use with dairy products, antacids, or iron/magnesium supplements (reduce absorption).

  • Complete the full course to prevent antibiotic resistance.

4. Side Effects

Common: Nausea, diarrhea, photosensitivity (sunburn risk).

• Serious:

  • Teeth discoloration & bone growth inhibition: Contraindicated in pregnancy, lactation, and children <8 years old.

  • Hepatotoxicity, kidney injury (with prolonged/high-dose use).

  • Clostridioides difficile-associated diarrhea (pseudomembranous colitis).

5. Contraindications & Interactions

• Contraindications:

  • Hypersensitivity to tetracyclines.

  • Pregnancy, breastfeeding, and pediatric patients (unless no alternatives exist).

• Drug interactions:

  • Antacids/divalent cations (Ca²?, Fe²?, Mg²?): Reduce absorption.

  • Oral contraceptives: May decrease contraceptive efficacy.

  • Warfarin: Potentiates anticoagulant effect (↑ bleeding risk).

6. Current Use & Alternatives

Largely replaced by second-generation tetracyclines (e.g., doxycycline, minocycline) due to rising resistance.

Still prescribed for acne (low-dose, long-term regimens).

Summary

Tetracycline hydrochloride remains a foundational antibiotic but is limited by resistance and adverse effects. Its hydrochloride form improves bioavailability. Clinical use requires caution in vulnerable populations (e.g., children, pregnant individuals) and adherence to dosing guidelines to balance efficacy and safety.