ISO&BVChina Factory Supply Melatonine 73-31-4 with lower price CAS NO.73-31-4

Product Name:    Melatonine
Synonyms:    Melatonin (AS);Melatonine,N-(2-(5-Methoxyindol-3-yl)ethyl)acetaMide;MELATONINE FOR SYNTHESIS 1 G;MELATONINE FOR SYNTHESIS 5 G;Melatonin solution ;N-[2-(5-METHOXY-1H-INDOL-3-YL)ETHYL]ACETAMIDE;N-(2-(5-methoxyindol-3-yl)ethyl)acetamide;MLT
CAS:    73-31-4
MF:    C13H16N2O2
MW:    232.28
EINECS:    200-797-7
Product Categories:    Inhibitors;bulk drug material;Heterocyclic Series;Heterocycles series;Indoles;Melatonin receptor;Tryptamines;Nutritional Supplements;Intermediates & Fine Chemicals;Pharmaceuticals;Amines;Heterocycles;Melatonins;Vitamin series;Alkaloid;Bioactive Small Molecules;Building Blocks;C13 to C27;Cell Biology;Cell Signaling and Neuroscience;Chemical Synthesis;Heterocyclic Building Blocks;M;Neurobiology;Neuroscience;Nutrition Research;Pharmacologicals;Phytochemicals by Chemical Classification;Herb extract;Other APIs;Melatonex;inhibitor;Cosmetics;cosmetics materials;73-31-4
Mol File:    73-31-4.mol

Melatonine Chemical Properties
Melting point     116.5-118 °C (lit.)
Boiling point     374.44°C (rough estimate)
density     1.1099 (rough estimate)
refractive index     1.6450 (estimate)
Fp     9℃
storage temp.     -20°C
solubility     Soluble in ethanol to at least 50mg/ml
form     Powder
pka    16.26±0.46(Predicted)
color     white to off-white
Merck     14,5816
BRN     205542
InChIKey    DRLFMBDRBRZALE-UHFFFAOYSA-N
CAS DataBase Reference    73-31-4(CAS DataBase Reference)
NIST Chemistry Reference    Melatonin(73-31-4)

description:Melatonin is a hormone secreted by the pineal gland, and its chemical structure was 5-methoxy-N-acetyl tryptamine, the physiological function of inhibiting gonad, thyroid, adrenal gland, parathyroid gland and pituitary function, inhibit precocious puberty, reduce pituitary Melanotropin secretion; and has a central nervous system function, can improve the convulsion the threshold, cause drowsiness. When pinealectomy after the animal experiment showed hyperplasia of the glands, weight increase, especially sex and sexual organs of immature rats early, pituitary secretion of LH and FSH increased, increasing secretion of thyroid and adrenal cortex hormone melatonin. More reduced pituitary MSH and whiten the skin of this role. Effects on the central nervous system, in the human EEG showed slow rhythm, increased seizure threshold, sleepiness, but does not affect their behavior and personality, of temporal lobe epilepsy and Ba Jinsen disease can reduce the motor nerve Abnormal EEG changes.

Uses:1. Melatonin can be used as medicine health care products, so as to enhance peoples immune function, preventing aging and back to youth. What’s more, it is also a kind of natural “sleeping pill”.
2. Melatonin is a kind of hormone secreted by pineal body of pituitary gland in the body. The amount of melatonin has something to do with light. The weaker the light is, the more the melatonin is, whereas the less. In addition, it is helpful to one’s sleep.
3. Biochemical research.

Synthesis of Melatonin:    Pineal cells obtain tryptophan from blood circulation and become 5-hydroxytryptophane catalyzed by hydroxylase and 5-hydroxytryptophane turns into 5-hydroxytryptamine after decarboxylated by decarboxylase. There are three possible changes for 5-hydroxytryptamine: for the first part it may turn into 5-hydroxyl-benzpyrole acetic acid when deaminated by monoamine oxidase; for another part, some 5-hydroxytryptamine will leave the pineal cell and be taken in by sympathetic nerve ending and stored with neurotransmitter and noradrenalin; for the remaining part, the 5-hydroxytryptamine will be acetylated by N-acetyl-5-hydroxy tryptamine transferase and then be o-methoxy by hydroxylation indole-o-methyl converzyme, finally forming melatonin. After being synthesized, melatonin will be released by cells and enter into blood circulation through cerebrospinal fluid or directly, where noradrenalin may strengthen the synthesis, the speed of which depends on activity of hydroxylase in liver microsomes. Catalyzed by the hydroxylase, 6-hydroxylmelatonin is formed, soon afterwards it combines with glucuronic acid and sulfate, excreting through urine.

Uses:1. Melatonin can be used as medicine health care products, so as to enhance peoples immune function, preventing aging and back to youth. What’s more, it is also a kind of natural “sleeping pill”.
2. Melatonin is a kind of hormone secreted by pineal body of pituitary gland in the body. The amount of melatonin has something to do with light. The weaker the light is, the more the melatonin is, whereas the less. In addition, it is helpful to one’s sleep.
3. Biochemical research.

Synthesis of Melatonin:    Pineal cells obtain tryptophan from blood circulation and become 5-hydroxytryptophane catalyzed by hydroxylase and 5-hydroxytryptophane turns into 5-hydroxytryptamine after decarboxylated by decarboxylase. There are three possible changes for 5-hydroxytryptamine: for the first part it may turn into 5-hydroxyl-benzpyrole acetic acid when deaminated by monoamine oxidase; for another part, some 5-hydroxytryptamine will leave the pineal cell and be taken in by sympathetic nerve ending and stored with neurotransmitter and noradrenalin; for the remaining part, the 5-hydroxytryptamine will be acetylated by N-acetyl-5-hydroxy tryptamine transferase and then be o-methoxy by hydroxylation indole-o-methyl converzyme, finally forming melatonin. After being synthesized, melatonin will be released by cells and enter into blood circulation through cerebrospinal fluid or directly, where noradrenalin may strengthen the synthesis, the speed of which depends on activity of hydroxylase in liver microsomes. Catalyzed by the hydroxylase, 6-hydroxylmelatonin is formed, soon afterwards it combines with glucuronic acid and sulfate, excreting through urine.

Packing & Shipping

FAQ

1. Do you have stock
As we know, most customers prefer stock, so we will try to keep stock for some products.
2. Could you please provide some samples
In order to facilitate transaction, it's my pleasure to provide you samples.
3. How should I pay
We accept various payment terms such as L/C,T/T, and Money Gram.
4. Is there a discount
Different quantity has different discount.
5. What’s your MOQ
Different products have different MOQ, such as:
1).Peptide products, the MOQ is 1 gram level.
2).Liquid products, the MOQ is usually 50-100ML.
3).API, the MOQ is 1KG.
4).Intermediate products and conventional product, the MOQ is 1KG; custom-tailored products, the MOQ depends on the production process.
5).Food additives and vitamin, the MOQ is usually one package: such as Vitamin C is 25KG/drum, Vitamin E oil or Vitamin A oil is 5KG/bag; Vitamin E powder or Vitamin A powder is 20KG/cartons.
6).Agrochemical, the MOQ is 1KG, except preparations.
6. How Should Package
Retail package with bottles, PE bags or foil bags in different sizes, or bulk package with drums, woven bags or pallets based on various requirement. LOGO service are available in all packages.

Company Information

Company profile
Wuhan Fortuna Chemical Co.,Ltd established in 2006, is a big integrative chemical enterprise being engaged in Pharmaceutical & its intermediates, Food/Feed additives, Fine chemicals in distributing the products of our own company and affiliated enterprises, are the members of Hubei E-commerce Chamber.
Our company has professional persons who major in chemical R&D and sicentific management, supply fine chemical products with high quality and close service, also supply custom-tailored products according to our clients’ requirement.
We have a positive and self-motivated management work team with a common philosophy, caring and commitment through teamwork, our team strive to achieve success in delighting our clients and ourselves. 
Since Wuhan Fortuna Chemical Co., Ltd founded, we continuously innovate our products and improve our service, sales network. Hence, we initiate the first sale mode on net in China, which is the retail trade of small package bring along wholesale of diversified management modes. Our products are exported widely to South Korea, Vietnam, Australia, Europe and South America, highly recommended by our clients.
We insist on the management creed “Market is our compass, Quality is our life, Credit is our soul”. Clients’ trust is our forward powder, their satisfaction is our struggling goal.

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